1) Purpose To investigate the pathologic characteristics of achondroplasia.

2) Energetic as Wan - yu is, she achondroplasia and is destined never to grow to an average size.

3) Genetic counselling and the management of complications in achondroplasia are important.

4) Twenty - five cases of achondroplasia followed for a period of recent three years are reviewed.

5) Their newborn daughter died last year from a devastating dwarfism - related disease called homozygous achondroplasia.

6) Conclusion The model of Fgfr 3 Gly 374 Arg mutation causing achondroplasia in mice has been established successfully.