1. Gratiano mischance ; the cry is very direful.

2. Gratiano. 'Tis some mischance; the cry is very direful.

3. Norris bases his direful prediction on a recent study he co-authored in the journal Nature along with Phil Sexton of the Open University in the United Kingdom, and other paleoclimatologists.

4. The surveyor's theodolite is one of the more direful symbols of the twentieth century.

5. A career or vengeance so direful that London was shocked.

6. What mind is there that does not shrink from its direful effects?