1. Myelodysplasia, which is associated with low platelet counts, predisposes some patients to leukemia.

2. In a study of 44 patients who had myelodysplasia and received Nplate, four patients developed leukemia.

3. Objective:To study the influence of neurogenic anorectum induced by myelodysplasia on function of anorectum.

4. It has been reported in association with acute myeloid leukemia, myeloproliferative disorders, and myelodysplasia in blast transformation, as well as in patients with no known hematological disorders.

5. Results 99 fetuses were obtained from the treated rats in the experimental group. Among the 99 fetuses, 48.3% (48/99)had major spina bifida and myelodysplasia.