1) The correlation of the exophthalmic extent, and the ratio of the global measurements to the orbital measurements were analyzed.

2) Conclusion GOP has similar value as GAP in estimating exophthalmic extent.

3) Two pathogenic bacteria of E-01 and L-01 strains were isolated from the eyes and livers of goldfish which suffered from the exophthalmic disease.

4) A pathogenic bacteria of RT E9801 strain was isolated from the eyes of red tilapia which suffered from the exophthalmic disease.

5) Objective evidences of the ophthalmocele may be provided by ultrasonography for diagnosing exophthalmic goiter.