1, OBJECTIVE: Paroxysmal nocturnal hemoglobinuria ( PNH ) is an acquired disease of the pluripotent hematopoitec stem cell.

2, Paroxysmal nocturnal hemoglobinuria often goes unrecognized - its diagnosis may be delayed for more than 10 years.

3, Objective:To detect the expression of glycosyl phosphatidyl inositol (GPI) anchored protein on the blood cell membrane and its implication in the diagnosis of paroxysmal nocturnal hemoglobinuria(PNH).

4, Objective To investigate the relationship between CD 59 and traditional hemolysis tests for paroxysmal nocturnal hemoglobinuria.

5, Although the dark urine may simply reflect dehydration, it could also reflect bilirubinuria or hemoglobinuria.

6, Objective : To study the effect of T - lymphocytes on hematopoietic progenitors in patients with paroxysmal hemoglobinuria ( PNH ).

7, The change of structure and function of erythrocytic membrane skeleton could be concluded that the most important factor in hemoglobinuria due to hypophosphatemia.