1. The two companies that make leucovorin, a generic cancer drug that's in short supply, are shedding some light on what's causing the shortage.

2. Leucovorin may also be used to prevent the side-effects of pyrimethamine.

3. Background Intravenous bolus fluorouracil plus leucovorin is the standard adjuvant treatment for colon cancer.

4. Injectable leucovorin, a generic drug, is a common part of chemotherapy treatment for colorectal cancer.

5. Objecktive To investigate the chemotherapeutic effect with high-dose leucovorin , 5-fluorouracil, diaminodichloride on the advanced and the first-treatment-failed esophageal carcinoma.

6. This study was conducted to establish a L615 mouse minimal residual leukemia model and examine the effect of calcium leucovorin (LV) on minimal residual leukemia (MRL).

7. To determine the maximum - tolerated dose (MTD) and dose - limiting toxicity (DLT) of iri-notecan (CPT-11), fluorouracil (5-FU), and leucovorin (CF) in patients with gastrointestinal cancers.

8. "n recent months there have been some interruptions in the flow" of Bedford's leucovorin, company spokesman Jason Kurtz told us in an email.

9. To evaluate the efficacy and side effect of navelbine (NVB) combined with cisplatin (DDP), leucovorin(CF) and 5-fluorouracil (5-FU) in the treatment of advanced esophageal carcinoma.