1 Virchow in 1851 presented a drawing of a multinucleate tumor cell.

2 Virchow, as the challenged party, had the choice of weapons.

3 In the early 1850's Virchow was led by the appearance of the tissue deposits of amyloid to suggest that it had a polysaccharide composition.

4 Otto von Bismarck, the Iron Chancellor, was once offended beyond endurance by a physician-turned-politician, Rudolf Virchow, and challenged him to a duel.

5 The disease was defined in 1845 by a German doctor, Rudolf Virchow, who looked at tumors taken at autopsy and said cancer is an uncontrolled growth that spreads and kills.