1, For some people, this includes sexual ones, including anorgasmia.

2, Anorgasmia may be psychologically induced, but could also be caused by other medical problems, such as multiple sclerosis, pelvic trauma, spinal cord injury, vulvodynia, or even a hormonal imbalance.

3, Only a fraction of anorgasmia cases come to the attention of clinicians, he said.

4, Teasing out the root cause of anorgasmia is another challenge.

5, To qualify as a disorder, anorgasmia, or the inability to orgasm, must be persistent and must interfere with the patient's quality of life or relationships.

6, It is hoped that by comparing the brain scans of women having an orgasm with those who cannot, scientists will be able to "coach" those with anorgasmia into truly "letting go".

7, Women who have never had an orgasm may be suffering from anorgasmia, also known as female orgasm disorder.

8, It is estimated that one in four women in the US has had difficulty achieving orgasm in the past year, while between five and ten percent of women suffer from anorgasmia and cannot climax at all.

9, Kidney disorders, fibromyalgia and atherosclerosis (the narrowing of arteries due to cholesterol buildup) are all associated with anorgasmia, the review found.