1 Summary of Background Data. Osteopetrosis is characterized by osteoclast dysfunction, impaired bone resorption, and poor bone remodeling.

2 Osteoblast and osteoclast activity in a malignant infantile osteopetrosis patient following bone marrow transplantation.

3 Methods The clinical data of 59 cases of osteopetrosis were analyzed retrospectively.

4 M-CSF is also widely used in the treatment of osteopetrosis and osteoclasts culture in vitro.

5 So it can be used in the treatment of osteopetrosis.

6 Conclusion. This case report discusses the rare occurrence of multiple lumbar pedicle fractures and pars interarticularis (spondylolysis) fractures in a patient with osteopetrosis.

7 Objective To investigate the features of genetic and clinical manifestation of osteopetrosis.

8 These bone-specific markers may be useful for the early assessment of malignant infantile osteopetrosis patients with stem cell transplantation.

9 The authors treated a 6-month-old boy with malignant infantile osteopetrosis using bone marrow transplantation.

10 Objective To discuss the clinical and pathological features of bone marrow biopsy of osteopetrosis.