(1) No correlation between gene transfection and fenestra formation or cleft of capillary endothelial cells was observed, and no apoptosis of endothelial cells was found.

(2) Objective To compare the effect of small fenestra stapedotomy and total stapedectomy in patients with otosclerosis.

(3) In method of fenestra cochleae, an electrical pole was inserted into the fenestra cochleae through the foramen stylomastoideum.

(4) Objective To compare the effect of fenestra stapedotomy and total stapedectomy in patients with otosclerosis.

(5) In section configuration, the depressions are either triangle or reversed trapezoid - fenestra structure.

(6) Conclusions The posterior and inferior quadrant of the footplate may be the optimal drill area for the fenestra.