(1) Voltaren is the trade name of the nonsteroidal anti - inflammatory drug that is administered only orally.

(2) Voltaren Gel was shown to cut pain in knee and hand osteoarthritis, states Novartis.

(3) The FDA approved Voltaren Gel based on studies that together included more than 900 patients with knee or hand osteoarthritis, according to Novartis, which makes Voltaren Gel.

(4) The most common side effects reported in clinical trials of Voltaren Gel were skin reactions; 7% of patients had reactions on the place where the gel was applied.

(5) Voltaren Gel contains diclofenac sodium, a nonsteroidal anti-inflammatory drug (NSAID) that's also in oral Voltaren. The gel can be applied to joints that hurt because of osteoarthritis.

(6) Methods:Through the mice hot plate test and tail pain tenderness test, compared to the control group and the positive drug Voltaren group to study the drug's analgesic effect.