(1) C. difficile causes pseudomembranous colitis, with potentially fatal diarrhea.

(2) Pseudomembranous colitis is caused by Clostridium difficile, and has become more common with increasing antibiotic use.

(3) Pseudomembranous colitis can usually be treated with oral vancomycin or metronidazole.

(4) Pseudomembranous colitis usually develops after antibiotics administration. The morbidity is gradually ascending.

(5) The key to prevent Pseudomembranous colitis is to administrate antibiotics rationally.

(6) Results Postoperative complications were observed in 6 cases (7.7%), including hemiplegia in 4 cases (1 case with combination of aphasia), pseudomembranous enteritis in 1 case and hypopsia in 1 case.