1. Propamidine is a new fungicide.

2. In prophase research of antifungi activity, propamidine has been found with high inhibitory effect against Botrytis cinerea.

3. Propamidine, which have novel effect on grey mould caused by Botrytis cinerea, is type of fungicide with intellectual property in China and it is safe to environment.

4. Physiological and biochemical mechanism of Botrytis cinerea resistance to propamidine was clarified preliminarily.

5. Synthesis, fungicidal activity, application current situation and prospect of propamidine were reviewed in this article.